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A Biomarker and Therapeutic Target for Early Onset Preeclampsia Brain Injury
Major morbidity and mortality associated with preeclampsia occurs as a result of brain injury and neurological complications, such as seizure, and occur more often in early onset preeclampsia (EPE). Researchers at UVM have identified a biomarker that arises in women with EPE and has been shown to increase both blood brain barrier (BBB) permeability...
Published: 2/4/2025   |   Inventor(s): Marilyn Cipolla
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Increase in Vasodilation in Small Vessel Disease Treated with Relaxin
Hypertension is a major risk factor for cerebral small vessel disease (SVD), a leading cause of progressive cognitive decline and a major risk factor for stroke. In pregnancy, relaxin promotes selective outward remodeling of parenchymal arterioles (PA) and increases capillary density in the brain specifically through the activation of peroxisome proliferator-activated...
Published: 2/4/2025   |   Inventor(s): Marilyn Cipolla
Keywords(s):  
Category(s): Technology Classifications > Biomedical
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